Pathology: A sharply demarcated region of emphysema; a gas-containing space that may contain nothing but gas or may contain overdistended and ruptured alveolar septa and blood vessels
Plain Radiograph: A sharply demarcated area of avascularity within the lung, measuring 1.0cm or more in diameter and possessing a wall less than 1mm in thickness - this is the preferred term fo all thin-walled air-containing spaces in the lung with the exception of pneumatocele
On CT, a bulla is a round, focal air space, 1cm or more in diameter, demarcated by a thin wall; usually multiple or assocated with other signs of pulmonary emphysema
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