This article from Boston, by Nielson J et al, in Circulation, describes the use of CMR in assessing the severity of coarctation of the aorta.
Their results are as follows:
"By logistic regression analysis, the following variables simultaneously predicted coarctation gradient
20 mm Hg: (1) smallest aortic cross-sectional area (adjusted for body surface area) measured by planimetry from gadolinium-enhanced 3D magnetic resonance angiography (OR 1.71 for 10 mm2/m2 decrease, P=0.005) and (2) heart rate–corrected mean flow deceleration in the descending aorta measured by phase-velocity cine MRI (OR 1.68 for 100 mL/s1.5 increase, P=0.018). For the combination of these variables, a predicted probability >0.38 had 95% sensitivity, 82% specificity, 90% positive and negative predictive values, and an area under the receiver-operator characteristics curve of 0.938. In a subsequent validation study, the prediction model correctly classified 9 of 10 patients, with no false-negatives."
In effect, CMR in nine out of 10 patients, using a combination of planimetry and flow measurements was able to predict the need for intervention, using the criterion of a pressure gradient of 20mmHg or more, as measured by cardiac catheterization.
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