Two new articles on the accuracy of 16-slice CT with a 375ms rotation tube have been published in JACC in the early part of this year. The first is by Mollet Nico et al from Erasmus University, Rotterdam and the other by Kuettner Axel et al from Tubingen. At both these centres, the scanners on which these studies were performed, no longer exist. They have now been superseded by 64-slice scanners with 330ms rotation tubes and the results from both these centres on the new scanners are better than the ones published using the older scanners. These new results were presented at the recent ECR held last month.
Mollet et al's study is of 51 patients where catheter angiography was the gold standard and the negative predictive value for detection of significant lesions on a segment-based analysis was 99%. The positive predictive value was 87%.
In the second study by Kuettner et al, 72 patients were studied and their negative predictive value for the whole study group was also 97%.
This is again in line with our own experience. A study published at our centre (Bajaj et al, unpublished) on 50 consecutive patients, showed a negative predictive value of 97% as well.